Faulty gene linked to depression and cardiovascular disease
A team led by the University of Adelaide's Discipline of Psychiatry has reviewed and attempted to replicate the findings of the growing body of research showing the types of genes expressed in the brain and surrounding tissues during depression. The findings -- published online ahead of print in the journal Neuroscience & Biobehavioral Reviews -- have supported multiple theories of the underlying genetic causes of depression, and have highlighted one gene that until now has gone under the radar in relation to mood disorders. "Depression is much more complex than most people think, and it includes dysfunction at multiple biological levels, from genes to brain regions, and blood circulating through the body," says Professor Bernhard Baune, Head of Psychiatry at the University of Adelaide and lead author of the paper. "The state of depression can also change over time, it goes through various phases and it may present with a large range of symptoms. ...